Please read the instructions carefully and use under the guidance of a physician
Generic name: Trappidil tablets
English name: Trapidil Tables
Chinese Pinyin: Qupidi’er Pian
[Ingredients] The main ingredient of this product is trampidil
Chemical name: 5-methyl-7-diethylamino-1,2,4-triazole[1,5-α]pyrimidine
Chemical structural formula: as shown on the right
Molecular formula: C10H15N5
Molecular weight: 205.26
[Properties] This product is white or off-white flakes.
【Indications】Used to treat and prevent coronary heart disease, angina pectoris, myocardial infarction, etc.
[Usage and Dosage] Oral, 50-100mg (1-2 tablets) once, 3 times a day, or follow the doctor's advice.
[Adverse reactions] Occasionally, headache, nausea, and palpitations may occur, which can be relieved by itself after dose reduction or withdrawal. When skin and mucous membranes and eye syndromes occur, stop taking it immediately, and make corresponding treatment under the guidance of a doctor.
[Contraindications] 1. It is forbidden for those who have not stopped intracranial hemorrhage.
2. People who are allergic to this product are prohibited.
3. It is forbidden for pregnant and lactating women.
[Precautions] Use with caution in patients with liver disease. If the liver function GOT and GPT rise abnormally after medication, stop taking it.
[Medicine for pregnant women and lactating women] This product can enter the placenta and inhibit the development of the fetus when taken in high doses (240mg/kg). This product can be secreted from milk, enter the baby's body, and affect the baby's development. Therefore, it is forbidden for pregnant and breastfeeding women.
【Children's Medication】The experiment has not been carried out and there is no reliable reference.
[Medication for the elderly] The experiment has not been conducted and there is no reliable reference.
[Drug Interactions] It is not clear yet.
[Drug overdose] Overdose (greater than 15g) will cause severe shock, lethargy, repeated vomiting, body cramps, drop in blood pressure, difficulty breathing, cold limbs, etc. In the event of drug overdose, first follow general drug poisoning enema, diuresis, etc., followed by hemodialysis, which can quickly improve clinical symptoms. In addition, special care should be taken in the treatment of patients with microcirculation collapse.
[Pharmacology and Toxicology] This product can inhibit the activity of cAMP phosphodiesterase, the effect of dilating coronary arteries is stronger than that of nitroglycerin, which is conducive to the establishment of collateral circulation; inhibits the synthesis of thromboxane A (TXA2) and promotes the production of prostacyclin (PGI2) It can expand peripheral arteries and veins to inhibit platelet aggregation, prevent platelet aggregation induced by arachidonic acid and platelets itself, and deaggregate the formed aggregation; this product can also competitively antagonize platelet-derived growth factor (PDGF) Receptors, inhibit the proliferation of smooth muscle cells.
[Pharmacokinetics] After oral administration in adults, the blood concentration rises rapidly, the peak time (tmax) is 2 hours, and the half-life (t1/2) is 6 hours. Metabolites can be detected in urine, and urine excretion at 72 hours is 30% of the dosage.
[Storage] shading, sealed and preserved.
[Packaging] PVC solid medicinal tablets, aluminum foil for medicine packaging. 18 pieces/plate×1 plate/box.
[Approval number] National Medicine Standard H20184139
Company Name: Hubei Meilin Pharmaceutical Co., Ltd.
Production address: Heping Road, Economic Development Zone, Yunmeng County, Xiaogan City, Hubei Province
Postal Code: 432500
Phone number: 0712-4226308
Fax number: 0712-4232879
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Company address：No. 8 Heping Road, Economic Development Zone, Yunmeng County, Xiaogan, Hubei Postal code：432500 This website supports IPV6
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